Mucoadhesive polymers for buccal drug delivery system: An overview

Pharmaceutical scientists around the globe have been seeking to discover as an alternative injections over last few, transdermal and transmucosal routes decades. The buccal cavity mucosa most convenient easily available site for distribution of local systemic therapeutic agents was found be dosage forms among numerous sitesavailable.Theories various polymers used in mucoadhesive drug delivery. Mucoadhesive increases residence time, prolong absorption, enhances solubilityand dissolution characteristics poorly soluble drugs. In addition, we are focused on latest generation mucoadhesion polymers, led by formulation oral drugs, such thiolated polymers. A good insight into phenomenon factors that can affect polymer is given current analysis. systematic delivery has investigated treatment or therapy subjected first pass metabolism. Oral discussing structural features mucosa, mechanism mucoadhesion. General consideration design forms, permeation enhancers evalution method along with literature survey mucoadhesive.